U.S. Accelerates Shift Away From Animal Testing as AI and Human-Based Models Reshape Drug Research 

The U.S. Department of Health and Human Services is accelerating a major transformation in biomedical research, launching new initiatives intended to reduce reliance on animal testing while expanding the use of human cells, organoids, organs-on-chips, artificial intelligence and computational models in drug development. The effort represents one of the federal government’s most significant moves toward […]

U.S. Seeks $30 Billion Aviation Overhaul After Major Failures Expose Aging Air Traffic System 

The Trump administration is preparing to ask Congress for another $30 billion to modernize the U.S. aviation system, dramatically expanding an effort to replace aging air-traffic-control technology after a series of failures disrupted thousands of flights and exposed vulnerabilities in critical national infrastructure. Transportation Secretary Sean Duffy said the additional money would be divided among […]

Los Angeles Needs Thousands of Apartments, but Developers Say Building Them No Longer Pays 

Los Angeles is confronting a striking contradiction in its housing crisis: the city desperately needs more apartments, but many developers say constructing them has become financially unattractive. Despite persistent housing shortages and high rents, multifamily construction is slowing as developers confront elevated interest rates, falling apartment values, rising construction expenses, regulatory costs and taxes that […]

U.S. Expands Its Arctic Military Footprint in Landmark Greenland Security Deal

The United States, Denmark and Greenland have signed a major new security agreement that significantly expands the American military presence on Greenland while leaving sovereignty over the strategically important Arctic territory unchanged. The agreement represents an effort to resolve months of diplomatic tension generated by President Donald Trump’s repeated demands for greater American control over […]

Meta’s Massive Network Gives Zuckerberg the Freedom to Fail Until the Next Big Idea Works

Mark Zuckerberg has survived a remarkable series of expensive technological bets, controversies and strategic mistakes, yet Meta continues to emerge with new opportunities for growth. The latest example is Muse, the company’s new artificial-intelligence assistant, whose rapid popularity demonstrates Meta’s greatest competitive advantage: an enormous global network that gives the company repeated chances to experiment. […]

Potent Kratom Products Drive a New Wave of Addiction and Severe Withdrawal Across the U.S.

Addiction treatment centers across the United States are reporting a sharp increase in patients seeking help for dependence on kratom and, increasingly, highly concentrated products containing 7-hydroxymitragynine, or 7-OH. Kratom comes from the leaves of a tree native to Southeast Asia and has been available in the United States for decades. Traditionally sold as powders, […]

Pablo Ferrer Saez and Capital Street Are Bringing Institutional-Level Market Expertise to a Wider Audience

As artificial intelligence continues to reshape the financial sector, veteran market professional Pablo Ferrer Saez is betting that the future of investing will be defined by a combination of technology, experience and greater accessibility. Ferrer Saez, founder of Capital Street, has spent more than 20 years working in financial markets, gaining experience across banks, asset-management-related […]

California’s Insurance Crisis Spreads Beyond Wildfire Zones as Homeowners Run Out of Options 

California’s property insurance crisis is expanding beyond the mountainous and heavily wooded communities traditionally considered most vulnerable to wildfires, leaving homeowners in relatively low-risk suburban neighborhoods struggling to obtain conventional coverage. An analysis of insurance data found that major insurers are increasingly declining to write policies across large portions of the state, including rapidly growing […]

Telix Makes $2.35 Billion Bet on ITM to Build a Global Powerhouse in Cancer Radiopharmaceuticals 

Telix Pharmaceuticals has agreed to merge with Germany’s ITM Isotope Technologies Munich in a transaction potentially worth $2.35 billion, a major expansion designed to strengthen Telix’s position in the rapidly growing market for radioactive medicines used to diagnose and treat cancer. The combination brings together two complementary businesses. Australia-based Telix develops radiopharmaceuticals for cancer imaging […]

Trump Transforms U.S. Refugee Office Into a $410 Million Global Deportation Network 

The Trump administration has dramatically transformed a State Department bureau historically dedicated to refugees and humanitarian assistance into a central component of its immigration enforcement strategy, building a global network of agreements that allows the United States to deport migrants to countries where they have never lived. At the center of the transformation is the […]